Although the relative contribution of MCT1 and SMCT1 into the renal reabsorption of GHB has not been identified in vivoCells produce GHB by reduction of succinic semialdehyde via succinic semialdehyde reductase (SSR). This enzyme seems to get induced by cAMP ranges,[eighty] meaning substances that elevate cAMP, for instance forskolin and vinpocetin